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KMID : 0853020140170020061
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Journal of Korean Burn Society
2014 Volume.17 No. 2 p.61 ~ p.64
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Vitamin C and D Insufficiency in Burn Patients Un-dergoing Rehabilitative Therapy-Preliminary Result
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Cho Yun-Soo
Choi Young-A
Seo Cheong-Hoon
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Abstract
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Purpose: The burn increase the requirement for the antioxi-dative vitamin C and decrease the plasma concentration of vitamin D due to the loss of skin body surface area. We inves-tigated the vitamin C and D status and the prevalence of vita-min C and D insufficiency in adult burn patients undergoing rehabilitative therapy.
Methods: 256 burn patients admitted to the department of rehabilitation medicine from April 2013 to September 2014 were tested for the plasma level of vitamin C and D[25(OH)D]. Vitamin C insufficiency was considered as ＜26.1μmol/L and vitamin D insufficiency as ＜20 ng/ml. We compared the mean plasma level of vitamin C and D[25(OH)D] according to burned percent of total body surface area (TBSA).
Results: Vitamin C insufficiency in 63.3% and vitamin D defi-ciency in 87.1%. In burn patients of TBSA≥20%, mean plasma concentration of vitamin C and vitamin D[25(OH)D] were sig-nificantly lower (P=0.023, P＜0.001). With adjusting for poten-tial confounder such as age, sex, burn type, mean serum 25 (OH)D levels was significantly decreased 0.07 ng/ml per one percent of burned surface area (β=?0.07, P＜0.001), but with adjusting for age, sex, burn type, length of ICU stay and duration from burn injury to sampling, vitamin C and vitamin D[25(OH)D] were not significantly decreased (P=0.221, P=0.142).
Conclusion: Vitamin C and D insufficiency were common nu-trient problems in burn patients undergoing rehabilitative therapy. Further studies will be needed to establish the effec-tive way to improve vitamin C and D status and prevent nutri-tional complications.
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KEYWORD
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Vitamin C, Vitamin D, Burn
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